L-Naloxone
Brand names,
L-Naloxone
Analogs
L-Naloxone
Brand Names Mixture
L-Naloxone
Chemical_Formula
C19H21NO4
L-Naloxone
RX_link
http://www.rxlist.com/cgi/generic3/naloxone.htm
L-Naloxone
fda sheet
L-Naloxone
msds (material safety sheet)
L-Naloxone
Synthesis Reference
No information avaliable
L-Naloxone
Molecular Weight
327.374 g/mol
L-Naloxone
Melting Point
200 - 205 oC
L-Naloxone
H2O Solubility
Soluble
L-Naloxone
State
Solid
L-Naloxone
LogP
1.464
L-Naloxone
Dosage Forms
Liquid
L-Naloxone
Indication
For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol.
L-Naloxone
Pharmacology
Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the "agonistic" or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.
L-Naloxone
Absorption
Well absorbed following intramuscular injection.
L-Naloxone
side effects and Toxicity
No information avaliable
L-Naloxone
Patient Information
No information avaliable
L-Naloxone
Organisms Affected
Humans and other mammals