Naloxona [Inn-Spanish]
Brand names,
Naloxona [Inn-Spanish]
Analogs
Naloxona [Inn-Spanish]
Brand Names Mixture
Naloxona [Inn-Spanish]
Chemical_Formula
C19H21NO4
Naloxona [Inn-Spanish]
RX_link
http://www.rxlist.com/cgi/generic3/naloxone.htm
Naloxona [Inn-Spanish]
fda sheet
Naloxona [Inn-Spanish]
msds (material safety sheet)
Naloxona [Inn-Spanish]
Synthesis Reference
No information avaliable
Naloxona [Inn-Spanish]
Molecular Weight
327.374 g/mol
Naloxona [Inn-Spanish]
Melting Point
200 - 205 oC
Naloxona [Inn-Spanish]
H2O Solubility
Soluble
Naloxona [Inn-Spanish]
State
Solid
Naloxona [Inn-Spanish]
LogP
1.464
Naloxona [Inn-Spanish]
Dosage Forms
Liquid
Naloxona [Inn-Spanish]
Indication
For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol.
Naloxona [Inn-Spanish]
Pharmacology
Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the "agonistic" or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.
Naloxona [Inn-Spanish]
Absorption
Well absorbed following intramuscular injection.
Naloxona [Inn-Spanish]
side effects and Toxicity
No information avaliable
Naloxona [Inn-Spanish]
Patient Information
No information avaliable
Naloxona [Inn-Spanish]
Organisms Affected
Humans and other mammals