Nalone
Brand names,
Nalone
Analogs
Nalone
Brand Names Mixture
Nalone
Chemical_Formula
C19H21NO4
Nalone
RX_link
http://www.rxlist.com/cgi/generic3/naloxone.htm
Nalone
fda sheet
Nalone
msds (material safety sheet)
Nalone
Synthesis Reference
No information avaliable
Nalone
Molecular Weight
327.374 g/mol
Nalone
Melting Point
200 - 205 oC
Nalone
H2O Solubility
Soluble
Nalone
State
Solid
Nalone
LogP
1.464
Nalone
Dosage Forms
Liquid
Nalone
Indication
For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol.
Nalone
Pharmacology
Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the "agonistic" or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.
Nalone
Absorption
Well absorbed following intramuscular injection.
Nalone
side effects and Toxicity
No information avaliable
Nalone
Patient Information
No information avaliable
Nalone
Organisms Affected
Humans and other mammals