Narcan
Brand names,
Narcan
Analogs
Narcan
Brand Names Mixture
Narcan
Chemical_Formula
C19H21NO4
Narcan
RX_link
http://www.rxlist.com/cgi/generic3/naloxone.htm
Narcan
fda sheet
Narcan
msds (material safety sheet)
Narcan
Synthesis Reference
No information avaliable
Narcan
Molecular Weight
327.374 g/mol
Narcan
Melting Point
200 - 205 oC
Narcan
H2O Solubility
Soluble
Narcan
State
Solid
Narcan
LogP
1.464
Narcan
Dosage Forms
Liquid
Narcan
Indication
For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol.
Narcan
Pharmacology
Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the "agonistic" or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.
Narcan
Absorption
Well absorbed following intramuscular injection.
Narcan
side effects and Toxicity
No information avaliable
Narcan
Patient Information
No information avaliable
Narcan
Organisms Affected
Humans and other mammals