Narcanti
Brand names,
Narcanti
Analogs
Narcanti
Brand Names Mixture
Narcanti
Chemical_Formula
C19H21NO4
Narcanti
RX_link
http://www.rxlist.com/cgi/generic3/naloxone.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
327.374 g/mol
Narcanti
Melting Point
200 - 205 oC
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H2O Solubility
Soluble
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State
Solid
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LogP
1.464
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Dosage Forms
Liquid
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Indication
For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol.
Narcanti
Pharmacology
Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the "agonistic" or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.
Narcanti
Absorption
Well absorbed following intramuscular injection.
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals