Narcotic Antagonist
Brand names,
Narcotic Antagonist
Analogs
Narcotic Antagonist
Brand Names Mixture
Narcotic Antagonist
Chemical_Formula
C19H21NO4
Narcotic Antagonist
RX_link
http://www.rxlist.com/cgi/generic3/naloxone.htm
Narcotic Antagonist
fda sheet
Narcotic Antagonist
msds (material safety sheet)
Narcotic Antagonist
Synthesis Reference
No information avaliable
Narcotic Antagonist
Molecular Weight
327.374 g/mol
Narcotic Antagonist
Melting Point
200 - 205 oC
Narcotic Antagonist
H2O Solubility
Soluble
Narcotic Antagonist
State
Solid
Narcotic Antagonist
LogP
1.464
Narcotic Antagonist
Dosage Forms
Liquid
Narcotic Antagonist
Indication
For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol.
Narcotic Antagonist
Pharmacology
Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the "agonistic" or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.
Narcotic Antagonist
Absorption
Well absorbed following intramuscular injection.
Narcotic Antagonist
side effects and Toxicity
No information avaliable
Narcotic Antagonist
Patient Information
No information avaliable
Narcotic Antagonist
Organisms Affected
Humans and other mammals