Morphin
Brand names,
Morphin
Analogs
Morphin
Brand Names Mixture
Morphin
Chemical_Formula
C18H21NO3
Morphin
RX_link
http://www.rxlist.com/cgi/generic/codphos.htm
Morphin
fda sheet
Morphin
msds (material safety sheet)
Morphin
Synthesis Reference
Goto, Yamamoto, Proc. Japan Acad. 30, 769 (1954)
Morphin
Molecular Weight
299.364 g/mol
Morphin
Melting Point
154 - 156 oC
Morphin
H2O Solubility
<0.1 g/100 mL
Morphin
State
solid
Morphin
LogP
1.809
Morphin
Dosage Forms
Oral solution; Tablet
Morphin
Indication
For treatment and management of pain (Systemic), also used as an Antidiarrheal and as a cough suppressant.
Morphin
Pharmacology
Codeine, an opiate agonist in the CNS, is similar to other phenanthrene derivatives such as morphine. Codeine, in combination with guaifenesin or iodinated glycerol, is used as a cough suppressant and, as a single agent or in combination with acetaminophen or other products, is used for pain control and as an antidiarrheal agent.
Morphin
Absorption
well absorbed
Morphin
side effects and Toxicity
Respiratory depression, sedation and miosis and common symptoms of overdose. Other symptoms include nausea, vomiting, skeletal muscle flaccidity, bradycardia, hypotension, and cool, clammy skin. Apnea and death may ensue
Morphin
Patient Information
Codeine may impair the mental and/or physical abilities required for the performance of potentially hazardous
tasks, s.c. as driving a car or operating machinery. Codeine in combination with other narcotic analgesics,
phenothiazines, sedative hypnotics, and alcohol has additive depressant effects.
Morphin
Organisms Affected
Humans and other mammals