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Metformin Brand names, Metformin Analogs

Metformin Brand Names Mixture

  • No information avaliable

Metformin Chemical_Formula


Metformin RX_link

Metformin fda sheet

Metformin FDA

Metformin msds (material safety sheet)

Metformin MSDS

Metformin Synthesis Reference

No information avaliable

Metformin Molecular Weight

129.164 g/mol

Metformin Melting Point

223-226 oC

Metformin H2O Solubility

Freely soluble as HCl salt

Metformin State


Metformin LogP


Metformin Dosage Forms

Extended release tablet (500 mg or 1000 mg)

Metformin Indication

For use as an adjunct to diet and exercise to improve glycemic control in adult patients (18 years and older) with type 2 diabetes.

Metformin Pharmacology

Metformin is an antihyperglycemic agent, which improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Metformin is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. Unlike sulfonylureas, metformin does not produce hypoglycemia in either patients with type 2 diabetes or normal subjects and does not cause hyperinsulinemia. With metformin therapy, insulin secretion remains unchanged while fasting insulin levels and daylong plasma insulin response may actually decrease.

Metformin Absorption

Absorbed over 6 hours, bioavailability is 50 to 60% under fasting conditions. Food delays absorption.

Metformin side effects and Toxicity

Acute oral toxicity (LD50): 350 mg/kg [Rabbit]. It would be expected that adverse reactions of a more intense character including epigastric discomfort, nausea, and vomiting followed by diarrhea, drowsiness, weakness, dizziness, malaise and headache might be seen.

Metformin Patient Information

Metformin Organisms Affected

Humans and other mammals