Menhydrinate
Brand names,
Menhydrinate
Analogs
Menhydrinate
Brand Names Mixture
Menhydrinate
Chemical_Formula
C17H22N2O
Menhydrinate
RX_link
No information avaliable
Menhydrinate
fda sheet
Menhydrinate
msds (material safety sheet)
Menhydrinate
Synthesis Reference
No information avaliable
Menhydrinate
Molecular Weight
270.369 g/mol
Menhydrinate
Melting Point
< 25 oC
Menhydrinate
H2O Solubility
1 g/ml (succinate salt)
Menhydrinate
State
Liquid
Menhydrinate
LogP
2.755
Menhydrinate
Dosage Forms
Tablet for oral administration
Menhydrinate
Indication
Used alone as a short-term sleep aid, in combination with other drugs as a night-time cold and allergy relief drug. Also used in combination with Vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.
Menhydrinate
Pharmacology
Doxylamine is an antihistamine commonly used as a sleep aid. This drug is also used to relieve symptoms of hay fever (allergic rhinitis), hives (rash or itching), and other allergic reactions. Doxylamine is a member of the ethanolamine class of antihistamines and has anti-allergy power far superior to virtually every other antihistamine on the market, with the exception of diphenhydramine (Benadryl). It is also the most powerful over-the-counter sedative available in the United States, and more sedating than many prescription hypnotics. In a study, it was found to be superior to even the barbiturate, phenobarbital for use as a sedative. Doxylamine is also a potent anticholinergic.
Menhydrinate
Absorption
Readily absorbed via the gastrointestinal tract.
Menhydrinate
side effects and Toxicity
Signs of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, swelling of face, lips, tongue, or throat.
Menhydrinate
Patient Information
No information avaliable
Menhydrinate
Organisms Affected
Humans and other mammals