Gravol
Brand names,
Gravol
Analogs
Gravol
Brand Names Mixture
Gravol
Chemical_Formula
C17H22N2O
Gravol
RX_link
No information avaliable
Gravol
fda sheet
Gravol
msds (material safety sheet)
Gravol
Synthesis Reference
No information avaliable
Gravol
Molecular Weight
270.369 g/mol
Gravol
Melting Point
< 25 oC
Gravol
H2O Solubility
1 g/ml (succinate salt)
Gravol
State
Liquid
Gravol
LogP
2.755
Gravol
Dosage Forms
Tablet for oral administration
Gravol
Indication
Used alone as a short-term sleep aid, in combination with other drugs as a night-time cold and allergy relief drug. Also used in combination with Vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.
Gravol
Pharmacology
Doxylamine is an antihistamine commonly used as a sleep aid. This drug is also used to relieve symptoms of hay fever (allergic rhinitis), hives (rash or itching), and other allergic reactions. Doxylamine is a member of the ethanolamine class of antihistamines and has anti-allergy power far superior to virtually every other antihistamine on the market, with the exception of diphenhydramine (Benadryl). It is also the most powerful over-the-counter sedative available in the United States, and more sedating than many prescription hypnotics. In a study, it was found to be superior to even the barbiturate, phenobarbital for use as a sedative. Doxylamine is also a potent anticholinergic.
Gravol
Absorption
Readily absorbed via the gastrointestinal tract.
Gravol
side effects and Toxicity
Signs of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, swelling of face, lips, tongue, or throat.
Gravol
Patient Information
No information avaliable
Gravol
Organisms Affected
Humans and other mammals