L-Hyoscamine
Brand names,
L-Hyoscamine
Analogs
L-Hyoscamine
Brand Names Mixture
L-Hyoscamine
Chemical_Formula
C17H23NO3
L-Hyoscamine
RX_link
http://www.rxlist.com/cgi/generic/hyoscy.htm
L-Hyoscamine
fda sheet
L-Hyoscamine
msds (material safety sheet)
L-Hyoscamine
Synthesis Reference
Fodor et al., Acta Chem. Acad. Sci. Hung.28(4), 409 (1961)
L-Hyoscamine
Molecular Weight
289.369 g/mol
L-Hyoscamine
Melting Point
141oC
L-Hyoscamine
H2O Solubility
3.56 mg/mL
L-Hyoscamine
State
Solid
L-Hyoscamine
LogP
2.904
L-Hyoscamine
Dosage Forms
Tablets; Oral drops; Elixir; Injection
L-Hyoscamine
Indication
For treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease and rhinitis.
L-Hyoscamine
Pharmacology
L-Hyoscyamine, the active optical isomer of atropine (dl-hyoscyamine), is a tertiary amine anticholinergic gastrointestinal agent.
L-Hyoscamine
Absorption
Absorbed totally and completely by sublingual administration as well as oral administration.
L-Hyoscamine
side effects and Toxicity
Symptoms of overdose include headache, nausea, vomiting, blurred vision, dilated pupils, hot dry skin, dizziness, dryness of the mouth, difficulty in swallowing, and CNS stimulation. LD50=mg/kg(orally in rat)
L-Hyoscamine
Patient Information
L-Hyoscamine
Organisms Affected
Humans and other mammals