Duboisine
Brand names,
Duboisine
Analogs
Duboisine
Brand Names Mixture
Duboisine
Chemical_Formula
C17H23NO3
Duboisine
RX_link
http://www.rxlist.com/cgi/generic/hyoscy.htm
Duboisine
fda sheet
Duboisine
msds (material safety sheet)
Duboisine
Synthesis Reference
Fodor et al., Acta Chem. Acad. Sci. Hung.28(4), 409 (1961)
Duboisine
Molecular Weight
289.369 g/mol
Duboisine
Melting Point
141oC
Duboisine
H2O Solubility
3.56 mg/mL
Duboisine
State
Solid
Duboisine
LogP
2.904
Duboisine
Dosage Forms
Tablets; Oral drops; Elixir; Injection
Duboisine
Indication
For treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease and rhinitis.
Duboisine
Pharmacology
L-Hyoscyamine, the active optical isomer of atropine (dl-hyoscyamine), is a tertiary amine anticholinergic gastrointestinal agent.
Duboisine
Absorption
Absorbed totally and completely by sublingual administration as well as oral administration.
Duboisine
side effects and Toxicity
Symptoms of overdose include headache, nausea, vomiting, blurred vision, dilated pupils, hot dry skin, dizziness, dryness of the mouth, difficulty in swallowing, and CNS stimulation. LD50=mg/kg(orally in rat)
Duboisine
Patient Information
Duboisine
Organisms Affected
Humans and other mammals