Hyocyamine
Brand names,
Hyocyamine
Analogs
Hyocyamine
Brand Names Mixture
Hyocyamine
Chemical_Formula
C17H23NO3
Hyocyamine
RX_link
http://www.rxlist.com/cgi/generic/hyoscy.htm
Hyocyamine
fda sheet
Hyocyamine
msds (material safety sheet)
Hyocyamine
Synthesis Reference
Fodor et al., Acta Chem. Acad. Sci. Hung.28(4), 409 (1961)
Hyocyamine
Molecular Weight
289.369 g/mol
Hyocyamine
Melting Point
141oC
Hyocyamine
H2O Solubility
3.56 mg/mL
Hyocyamine
State
Solid
Hyocyamine
LogP
2.904
Hyocyamine
Dosage Forms
Tablets; Oral drops; Elixir; Injection
Hyocyamine
Indication
For treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease and rhinitis.
Hyocyamine
Pharmacology
L-Hyoscyamine, the active optical isomer of atropine (dl-hyoscyamine), is a tertiary amine anticholinergic gastrointestinal agent.
Hyocyamine
Absorption
Absorbed totally and completely by sublingual administration as well as oral administration.
Hyocyamine
side effects and Toxicity
Symptoms of overdose include headache, nausea, vomiting, blurred vision, dilated pupils, hot dry skin, dizziness, dryness of the mouth, difficulty in swallowing, and CNS stimulation. LD50=mg/kg(orally in rat)
Hyocyamine
Patient Information
Hyocyamine
Organisms Affected
Humans and other mammals