L-Atropine
Brand names,
L-Atropine
Analogs
L-Atropine
Brand Names Mixture
L-Atropine
Chemical_Formula
C17H23NO3
L-Atropine
RX_link
http://www.rxlist.com/cgi/generic/hyoscy.htm
L-Atropine
fda sheet
L-Atropine
msds (material safety sheet)
L-Atropine
Synthesis Reference
Fodor et al., Acta Chem. Acad. Sci. Hung.28(4), 409 (1961)
L-Atropine
Molecular Weight
289.369 g/mol
L-Atropine
Melting Point
141oC
L-Atropine
H2O Solubility
3.56 mg/mL
L-Atropine
State
Solid
L-Atropine
LogP
2.904
L-Atropine
Dosage Forms
Tablets; Oral drops; Elixir; Injection
L-Atropine
Indication
For treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease and rhinitis.
L-Atropine
Pharmacology
L-Hyoscyamine, the active optical isomer of atropine (dl-hyoscyamine), is a tertiary amine anticholinergic gastrointestinal agent.
L-Atropine
Absorption
Absorbed totally and completely by sublingual administration as well as oral administration.
L-Atropine
side effects and Toxicity
Symptoms of overdose include headache, nausea, vomiting, blurred vision, dilated pupils, hot dry skin, dizziness, dryness of the mouth, difficulty in swallowing, and CNS stimulation. LD50=mg/kg(orally in rat)
L-Atropine
Patient Information
L-Atropine
Organisms Affected
Humans and other mammals