Egazil
Brand names,
Egazil
Analogs
Egazil
Brand Names Mixture
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Chemical_Formula
C17H23NO3
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RX_link
http://www.rxlist.com/cgi/generic/hyoscy.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
Fodor et al., Acta Chem. Acad. Sci. Hung.28(4), 409 (1961)
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Molecular Weight
289.369 g/mol
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Melting Point
141oC
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H2O Solubility
3.56 mg/mL
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State
Solid
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LogP
2.904
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Dosage Forms
Tablets; Oral drops; Elixir; Injection
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Indication
For treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease and rhinitis.
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Pharmacology
L-Hyoscyamine, the active optical isomer of atropine (dl-hyoscyamine), is a tertiary amine anticholinergic gastrointestinal agent.
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Absorption
Absorbed totally and completely by sublingual administration as well as oral administration.
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side effects and Toxicity
Symptoms of overdose include headache, nausea, vomiting, blurred vision, dilated pupils, hot dry skin, dizziness, dryness of the mouth, difficulty in swallowing, and CNS stimulation. LD50=mg/kg(orally in rat)
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Patient Information
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Organisms Affected
Humans and other mammals