PharmacyCodes



Kanamycin en es it fr

Kanamycin Brand names, Kanamycin Analogs

Kanamycin Brand Names Mixture

  • No information avaliable

Kanamycin Chemical_Formula

C18H36N4O11

Kanamycin RX_link

http://www.rxlist.com/cgi/generic3/kanamycin.htm

Kanamycin fda sheet

Kanamycin msds (material safety sheet)

Kanamycin MSDS

Kanamycin Synthesis Reference

No information avaliable

Kanamycin Molecular Weight

484.499 g/mol

Kanamycin Melting Point

No information avaliable

Kanamycin H2O Solubility

No information avaliable

Kanamycin State

Solid

Kanamycin LogP

-7.936

Kanamycin Dosage Forms

No information avaliable

Kanamycin Indication

For treatment of infections where one or more of the following are the known or suspected pathogens: E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species.

Kanamycin Pharmacology

Kanamycin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.

Kanamycin Absorption

No information avaliable

Kanamycin side effects and Toxicity

LD 50 - ORAL, MOUSE = 17500 MG/KG, LD 50 - ORAL, RAT = >4 GM/KG, LD 50 - ORAL, RABBIT = >3 GM/KG

Kanamycin Patient Information

No information avaliable

Kanamycin Organisms Affected

Enteric bacteria and other eubacteria