Kanamycin Base
Kanamycin Base Brand names, Kanamycin Base Analogs
Kanamycin Base Brand Names Mixture
- No information avaliable
Kanamycin Base Chemical_Formula
C18H36N4O11
Kanamycin Base RX_link
http://www.rxlist.com/cgi/generic3/kanamycin.htm
Kanamycin Base fda sheet
Kanamycin Base msds (material safety sheet)
Kanamycin Base Synthesis Reference
No information avaliable
Kanamycin Base Molecular Weight
484.499 g/mol
Kanamycin Base Melting Point
No information avaliable
Kanamycin Base H2O Solubility
No information avaliable
Kanamycin Base State
Solid
Kanamycin Base LogP
-7.936
Kanamycin Base Dosage Forms
No information avaliable
Kanamycin Base Indication
For treatment of infections where one or more of the following are the known or suspected pathogens: E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species.
Kanamycin Base Pharmacology
Kanamycin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
Kanamycin Base Absorption
No information avaliable
Kanamycin Base side effects and Toxicity
LD 50 - ORAL, MOUSE = 17500 MG/KG, LD 50 - ORAL, RAT = >4 GM/KG, LD 50 - ORAL, RABBIT = >3 GM/KG
Kanamycin Base Patient Information
No information avaliable
Kanamycin Base Organisms Affected
Enteric bacteria and other eubacteria
