Nebramycin Factor 5
Brand names,
Nebramycin Factor 5
Analogs
Nebramycin Factor 5
Brand Names Mixture
Nebramycin Factor 5
Chemical_Formula
C18H36N4O11
Nebramycin Factor 5
RX_link
http://www.rxlist.com/cgi/generic3/kanamycin.htm
Nebramycin Factor 5
fda sheet
Nebramycin Factor 5
msds (material safety sheet)
Nebramycin Factor 5
Synthesis Reference
No information avaliable
Nebramycin Factor 5
Molecular Weight
484.499 g/mol
Nebramycin Factor 5
Melting Point
No information avaliable
Nebramycin Factor 5
H2O Solubility
No information avaliable
Nebramycin Factor 5
State
Solid
Nebramycin Factor 5
LogP
-7.936
Nebramycin Factor 5
Dosage Forms
No information avaliable
Nebramycin Factor 5
Indication
For treatment of infections where one or more of the following are the known or suspected pathogens: E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species.
Nebramycin Factor 5
Pharmacology
Kanamycin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
Nebramycin Factor 5
Absorption
No information avaliable
Nebramycin Factor 5
side effects and Toxicity
LD 50 - ORAL, MOUSE = 17500 MG/KG, LD 50 - ORAL, RAT = >4 GM/KG, LD 50 - ORAL, RABBIT = >3 GM/KG
Nebramycin Factor 5
Patient Information
No information avaliable
Nebramycin Factor 5
Organisms Affected
Enteric bacteria and other eubacteria