Kanamycin Sulfate
Kanamycin Sulfate Brand names, Kanamycin Sulfate Analogs
Kanamycin Sulfate Brand Names Mixture
- No information avaliable
Kanamycin Sulfate Chemical_Formula
C18H36N4O11
Kanamycin Sulfate RX_link
http://www.rxlist.com/cgi/generic3/kanamycin.htm
Kanamycin Sulfate fda sheet
Kanamycin Sulfate msds (material safety sheet)
Kanamycin Sulfate Synthesis Reference
No information avaliable
Kanamycin Sulfate Molecular Weight
484.499 g/mol
Kanamycin Sulfate Melting Point
No information avaliable
Kanamycin Sulfate H2O Solubility
No information avaliable
Kanamycin Sulfate State
Solid
Kanamycin Sulfate LogP
-7.936
Kanamycin Sulfate Dosage Forms
No information avaliable
Kanamycin Sulfate Indication
For treatment of infections where one or more of the following are the known or suspected pathogens: E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species.
Kanamycin Sulfate Pharmacology
Kanamycin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
Kanamycin Sulfate Absorption
No information avaliable
Kanamycin Sulfate side effects and Toxicity
LD 50 - ORAL, MOUSE = 17500 MG/KG, LD 50 - ORAL, RAT = >4 GM/KG, LD 50 - ORAL, RABBIT = >3 GM/KG
Kanamycin Sulfate Patient Information
No information avaliable
Kanamycin Sulfate Organisms Affected
Enteric bacteria and other eubacteria
