Aminodeoxykanamycin
Aminodeoxykanamycin Brand names, Aminodeoxykanamycin Analogs
Aminodeoxykanamycin Brand Names Mixture
- No information avaliable
Aminodeoxykanamycin Chemical_Formula
C18H36N4O11
Aminodeoxykanamycin RX_link
http://www.rxlist.com/cgi/generic3/kanamycin.htm
Aminodeoxykanamycin fda sheet
Aminodeoxykanamycin msds (material safety sheet)
Aminodeoxykanamycin Synthesis Reference
No information avaliable
Aminodeoxykanamycin Molecular Weight
484.499 g/mol
Aminodeoxykanamycin Melting Point
No information avaliable
Aminodeoxykanamycin H2O Solubility
No information avaliable
Aminodeoxykanamycin State
Solid
Aminodeoxykanamycin LogP
-7.936
Aminodeoxykanamycin Dosage Forms
No information avaliable
Aminodeoxykanamycin Indication
For treatment of infections where one or more of the following are the known or suspected pathogens: E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species.
Aminodeoxykanamycin Pharmacology
Kanamycin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
Aminodeoxykanamycin Absorption
No information avaliable
Aminodeoxykanamycin side effects and Toxicity
LD 50 - ORAL, MOUSE = 17500 MG/KG, LD 50 - ORAL, RAT = >4 GM/KG, LD 50 - ORAL, RABBIT = >3 GM/KG
Aminodeoxykanamycin Patient Information
No information avaliable
Aminodeoxykanamycin Organisms Affected
Enteric bacteria and other eubacteria
