Klebcil
Klebcil Brand names, Klebcil Analogs
Klebcil Brand Names Mixture
- No information avaliable
Klebcil Chemical_Formula
C18H36N4O11
Klebcil RX_link
http://www.rxlist.com/cgi/generic3/kanamycin.htm
Klebcil fda sheet
Klebcil msds (material safety sheet)
Klebcil Synthesis Reference
No information avaliable
Klebcil Molecular Weight
484.499 g/mol
Klebcil Melting Point
No information avaliable
Klebcil H2O Solubility
No information avaliable
Klebcil State
Solid
Klebcil LogP
-7.936
Klebcil Dosage Forms
No information avaliable
Klebcil Indication
For treatment of infections where one or more of the following are the known or suspected pathogens: E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species.
Klebcil Pharmacology
Kanamycin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
Klebcil Absorption
No information avaliable
Klebcil side effects and Toxicity
LD 50 - ORAL, MOUSE = 17500 MG/KG, LD 50 - ORAL, RAT = >4 GM/KG, LD 50 - ORAL, RABBIT = >3 GM/KG
Klebcil Patient Information
No information avaliable
Klebcil Organisms Affected
Enteric bacteria and other eubacteria
