KSR
Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C10H20O
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
156.265 g/mol
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Melting Point
43 oC
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H2O Solubility
0.49 mg/mL at 25 oC [CHEM INSPECT TEST INST (1992)]
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State
Solid
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LogP
3.211
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Dosage Forms
Cream; Drops; Gel; Globules; Jelly; Liquid; Lozenge; Ointment; Patch; Powder; Spray; Stick
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Indication
Used to treat occasional minor irritation, pain, sore mouth, and sore throat as well as cough associated with a cold or inhaled irritants.
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Pharmacology
Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Menthol's ability to chemically trigger cold-sensitive receptors in the skin is responsible for the well known cooling sensation that it provokes when inhalated, eaten, or applied to the skin. It should be noted that menthol does not cause an actual drop in temperature.
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Absorption
No information avaliable
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side effects and Toxicity
Menthol, DL: ORAL (LD50): Acute: 2900 mg/kg [Rat], 3100 mg/kg [Mouse]. DERMAL (LD50): Acute: 5001 mg/kg [Rabbit].
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Patient Information
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Organisms Affected
Humans and other mammals