Gestone
Brand names,
Gestone
Analogs
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Brand Names Mixture
- Calf-Oid Implant (Estradiol Benzoate + Progesterone)
- Component E-C Implants (Estradiol Benzoate + Progesterone)
- Component E-S Implants (Estradiol Benzoate + Progesterone)
- Component E-S Implants with Tylan (Estradiol Benzoate + Progesterone + Tylosin Tartrate)
- Synovex C (Calf Implants) (Estradiol Benzoate + Progesterone)
- Synovex S (Steer Implants) (Estradiol Benzoate + Progesterone)
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Chemical_Formula
C21H30O2
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RX_link
http://www.rxlist.com/cgi/generic/progesterone.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
314.462 g/mol
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Melting Point
121 oC
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H2O Solubility
8.81 mg/L
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State
Solid
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LogP
4.036
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Dosage Forms
Capsule; Gel; Implant; Liquid; Solution
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Indication
For progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency and for the treatment of secondary amenorrhea. Also used as a female contraceptive.
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Pharmacology
Progesterone is a progestin or a synthetic form of the naturally occurring female sex hormone, progesterone. In a woman's normal menstrual cycle, an egg matures and is released from the ovaries (ovulation). The ovary then produces progesterone, preventing the release of further eggs and priming the lining of the womb for a possible pregnancy. If pregnancy occurs, progesterone levels in the body remain high, maintaining the womb lining. If pregnancy does not occur, progesterone levels in the body fall, resulting in a menstrual period. Progesterone tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. This prevents the release of eggs from the ovaries.
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Absorption
Progesterone absorption is prolonged with an absorption half-life of approximately 25-50 hours.
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side effects and Toxicity
No information avaliable
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Patient Information
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Organisms Affected
Humans and other mammals