Gallaflex
Brand names,
Gallaflex
Analogs
Gallaflex
Brand Names Mixture
Gallaflex
Chemical_Formula
C24H45N3O3
Gallaflex
RX_link
No information avaliable
Gallaflex
fda sheet
Gallaflex
msds (material safety sheet)
Gallaflex
Synthesis Reference
No information avaliable
Gallaflex
Molecular Weight
423.633 g/mol
Gallaflex
Melting Point
147.5 oC
Gallaflex
H2O Solubility
Soluble
Gallaflex
State
Solid
Gallaflex
LogP
4.017
Gallaflex
Dosage Forms
Liquid
Gallaflex
Indication
For use as adjuncts to anesthesia to induce skeletal muscle relaxation and to facilitate the management of patients undergoing mechanical ventilation
Gallaflex
Pharmacology
Gallamine Triethiodide is a nondepolarizing neuromuscular blocking drug (NDMRD) used as an adjunct to anesthesia to induce skeletal muscle relaxation. The actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output. Muscle groups differ in their sensitivity to these types of relaxants with ocular muscles (controlling eyelids) being most sensitive, followed by the muscles of the neck, jaw, limbs and then abdomen. The diaphragm is the least sensitive muscle to NDMRDs. Although the nondepolarizing neuromuscular blocking drugs do not have the same adverse effects as succinylcholine, their onset of action is slower. They also have a longer duration of action, making them more suitable for maintaining neuromuscular relaxation during major surgical procedures.
Gallaflex
Absorption
No information avaliable
Gallaflex
side effects and Toxicity
No information avaliable
Gallaflex
Patient Information
No information avaliable
Gallaflex
Organisms Affected
Humans and other mammals