Gallamin
Brand names,
Gallamin
Analogs
Gallamin
Brand Names Mixture
Gallamin
Chemical_Formula
C24H45N3O3
Gallamin
RX_link
No information avaliable
Gallamin
fda sheet
Gallamin
msds (material safety sheet)
Gallamin
Synthesis Reference
No information avaliable
Gallamin
Molecular Weight
423.633 g/mol
Gallamin
Melting Point
147.5 oC
Gallamin
H2O Solubility
Soluble
Gallamin
State
Solid
Gallamin
LogP
4.017
Gallamin
Dosage Forms
Liquid
Gallamin
Indication
For use as adjuncts to anesthesia to induce skeletal muscle relaxation and to facilitate the management of patients undergoing mechanical ventilation
Gallamin
Pharmacology
Gallamine Triethiodide is a nondepolarizing neuromuscular blocking drug (NDMRD) used as an adjunct to anesthesia to induce skeletal muscle relaxation. The actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output. Muscle groups differ in their sensitivity to these types of relaxants with ocular muscles (controlling eyelids) being most sensitive, followed by the muscles of the neck, jaw, limbs and then abdomen. The diaphragm is the least sensitive muscle to NDMRDs. Although the nondepolarizing neuromuscular blocking drugs do not have the same adverse effects as succinylcholine, their onset of action is slower. They also have a longer duration of action, making them more suitable for maintaining neuromuscular relaxation during major surgical procedures.
Gallamin
Absorption
No information avaliable
Gallamin
side effects and Toxicity
No information avaliable
Gallamin
Patient Information
No information avaliable
Gallamin
Organisms Affected
Humans and other mammals