Triiodoethylate de Gallamine
Brand names,
Triiodoethylate de Gallamine
Analogs
Triiodoethylate de Gallamine
Brand Names Mixture
Triiodoethylate de Gallamine
Chemical_Formula
C24H45N3O3
Triiodoethylate de Gallamine
RX_link
No information avaliable
Triiodoethylate de Gallamine
fda sheet
Triiodoethylate de Gallamine
msds (material safety sheet)
Triiodoethylate de Gallamine
Synthesis Reference
No information avaliable
Triiodoethylate de Gallamine
Molecular Weight
423.633 g/mol
Triiodoethylate de Gallamine
Melting Point
147.5 oC
Triiodoethylate de Gallamine
H2O Solubility
Soluble
Triiodoethylate de Gallamine
State
Solid
Triiodoethylate de Gallamine
LogP
4.017
Triiodoethylate de Gallamine
Dosage Forms
Liquid
Triiodoethylate de Gallamine
Indication
For use as adjuncts to anesthesia to induce skeletal muscle relaxation and to facilitate the management of patients undergoing mechanical ventilation
Triiodoethylate de Gallamine
Pharmacology
Gallamine Triethiodide is a nondepolarizing neuromuscular blocking drug (NDMRD) used as an adjunct to anesthesia to induce skeletal muscle relaxation. The actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output. Muscle groups differ in their sensitivity to these types of relaxants with ocular muscles (controlling eyelids) being most sensitive, followed by the muscles of the neck, jaw, limbs and then abdomen. The diaphragm is the least sensitive muscle to NDMRDs. Although the nondepolarizing neuromuscular blocking drugs do not have the same adverse effects as succinylcholine, their onset of action is slower. They also have a longer duration of action, making them more suitable for maintaining neuromuscular relaxation during major surgical procedures.
Triiodoethylate de Gallamine
Absorption
No information avaliable
Triiodoethylate de Gallamine
side effects and Toxicity
No information avaliable
Triiodoethylate de Gallamine
Patient Information
No information avaliable
Triiodoethylate de Gallamine
Organisms Affected
Humans and other mammals