Flaxedil
Brand names,
Flaxedil
Analogs
Flaxedil
Brand Names Mixture
Flaxedil
Chemical_Formula
C24H45N3O3
Flaxedil
RX_link
No information avaliable
Flaxedil
fda sheet
Flaxedil
msds (material safety sheet)
Flaxedil
Synthesis Reference
No information avaliable
Flaxedil
Molecular Weight
423.633 g/mol
Flaxedil
Melting Point
147.5 oC
Flaxedil
H2O Solubility
Soluble
Flaxedil
State
Solid
Flaxedil
LogP
4.017
Flaxedil
Dosage Forms
Liquid
Flaxedil
Indication
For use as adjuncts to anesthesia to induce skeletal muscle relaxation and to facilitate the management of patients undergoing mechanical ventilation
Flaxedil
Pharmacology
Gallamine Triethiodide is a nondepolarizing neuromuscular blocking drug (NDMRD) used as an adjunct to anesthesia to induce skeletal muscle relaxation. The actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output. Muscle groups differ in their sensitivity to these types of relaxants with ocular muscles (controlling eyelids) being most sensitive, followed by the muscles of the neck, jaw, limbs and then abdomen. The diaphragm is the least sensitive muscle to NDMRDs. Although the nondepolarizing neuromuscular blocking drugs do not have the same adverse effects as succinylcholine, their onset of action is slower. They also have a longer duration of action, making them more suitable for maintaining neuromuscular relaxation during major surgical procedures.
Flaxedil
Absorption
No information avaliable
Flaxedil
side effects and Toxicity
No information avaliable
Flaxedil
Patient Information
No information avaliable
Flaxedil
Organisms Affected
Humans and other mammals