Fourneau 2559
Brand names,
Fourneau 2559
Analogs
Fourneau 2559
Brand Names Mixture
Fourneau 2559
Chemical_Formula
C24H45N3O3
Fourneau 2559
RX_link
No information avaliable
Fourneau 2559
fda sheet
Fourneau 2559
msds (material safety sheet)
Fourneau 2559
Synthesis Reference
No information avaliable
Fourneau 2559
Molecular Weight
423.633 g/mol
Fourneau 2559
Melting Point
147.5 oC
Fourneau 2559
H2O Solubility
Soluble
Fourneau 2559
State
Solid
Fourneau 2559
LogP
4.017
Fourneau 2559
Dosage Forms
Liquid
Fourneau 2559
Indication
For use as adjuncts to anesthesia to induce skeletal muscle relaxation and to facilitate the management of patients undergoing mechanical ventilation
Fourneau 2559
Pharmacology
Gallamine Triethiodide is a nondepolarizing neuromuscular blocking drug (NDMRD) used as an adjunct to anesthesia to induce skeletal muscle relaxation. The actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output. Muscle groups differ in their sensitivity to these types of relaxants with ocular muscles (controlling eyelids) being most sensitive, followed by the muscles of the neck, jaw, limbs and then abdomen. The diaphragm is the least sensitive muscle to NDMRDs. Although the nondepolarizing neuromuscular blocking drugs do not have the same adverse effects as succinylcholine, their onset of action is slower. They also have a longer duration of action, making them more suitable for maintaining neuromuscular relaxation during major surgical procedures.
Fourneau 2559
Absorption
No information avaliable
Fourneau 2559
side effects and Toxicity
No information avaliable
Fourneau 2559
Patient Information
No information avaliable
Fourneau 2559
Organisms Affected
Humans and other mammals