Flupenthixol
Brand names,
Flupenthixol
Analogs
Flupenthixol
Brand Names Mixture
Flupenthixol
Chemical_Formula
C23H25F3N2OS
Flupenthixol
RX_link
No information avaliable
Flupenthixol
fda sheet
Flupenthixol
msds (material safety sheet)
Flupenthixol
Synthesis Reference
P. N. Craig, C. L. Zirkle, U.S. pat. 3,282,930 (1966 to SKF)
Flupenthixol
Molecular Weight
434.519 g/mol
Flupenthixol
Melting Point
No information avaliable
Flupenthixol
H2O Solubility
0.000346 mg/ml
Flupenthixol
State
Solid
Flupenthixol
LogP
4.694
Flupenthixol
Dosage Forms
Tablet; IM injection
Flupenthixol
Indication
For use in the treatment of schizophrenia and depression
Flupenthixol
Pharmacology
Flupenthixol is an anxiolytic, antidepressive agent and a mood stabilizer. It inhibits the central monoamine receptors, particularly the dopamine D1 and D2 receptors. Therefore, it increases the amount of serotonin and noradrenaline that control mood and thinking, and improves mood.
Flupenthixol
Absorption
Fairly slow and incomplete after oral administration
Flupenthixol
side effects and Toxicity
LD50=300 mk/kg (Oral in mice); LD50=791 mg/kg (Oral in rats); LD50=87 mk/kg (IV in mice); LD50=37 mg/kg (IV in rats)
Flupenthixol
Patient Information
Patient Information:
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Flupenthixol
Organisms Affected
Humans and other mammals