Esomeprazole

Esomeprazole Brand names, Esomeprazole Analogs

Esomeprazole Brand Names Mixture

No information avaliable

Esomeprazole Chemical_Formula

C₁₇H₁₉N₃O₃S

Esomeprazole RX_link

http://www.rxlist.com/cgi/generic3/esomeprazole.htm

Esomeprazole fda sheet

Esomeprazole FDA

Esomeprazole msds (material safety sheet)

Esomeprazole Synthesis Reference

No information avaliable

Esomeprazole Molecular Weight

345.417 g/mol

Esomeprazole Melting Point

155 ^oC

Esomeprazole H₂O Solubility

Very slightly soluble in water

Esomeprazole State

Solid

Esomeprazole LogP

1.078

Esomeprazole Dosage Forms

Tablet (delayed-release); Delayed-release capsules; IV injection solution; IV iufusion solution

Esomeprazole Indication

For the treatment of acid-reflux disorders (GERD) and peptic ulcer disease

Esomeprazole Pharmacology

Esomeprazole is a compound that inhibits gastric acid secretion and is indicated in the treatment of gastroesophageal reflux disease (GERD), the healing of erosive esophagitis, and H. pylori eradication to reduce the risk of duodenal ulcer recurrence. Esomeprazole belongs to a new class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or H2 histamine antagonistic properties, but that suppress gastric acid secretion by specific inhibition of the H⁺/K⁺ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, Esomeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.

Esomeprazole Absorption

90%

Esomeprazole side effects and Toxicity

Blurred vision, confusion, drowsiness, dry mouthflushingheadache, nausea, rapid heartbeat, sweating

Esomeprazole Patient Information