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Diazoxide Brand names, Diazoxide Analogs

Diazoxide Brand Names Mixture

  • No information avaliable

Diazoxide Chemical_Formula

C8H7ClN2O2S

Diazoxide RX_link

No information avaliable

Diazoxide fda sheet

Diazoxide msds (material safety sheet)

Diazoxide MSDS

Diazoxide Synthesis Reference

No information avaliable

Diazoxide Molecular Weight

230.672 g/mol

Diazoxide Melting Point

330.5 oC

Diazoxide H2O Solubility

2850 mg/L

Diazoxide State

Solid

Diazoxide LogP

2.135

Diazoxide Dosage Forms

Oral capsules; Oral suspension

Diazoxide Indication

Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.

Diazoxide Pharmacology

Diazoxide is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. This switches off voltage-gated calcium ion channels which inhibits the generation of an action potential.

Diazoxide Absorption

Readily absorbed following oral administration.

Diazoxide side effects and Toxicity

Oral LD50 in rat and mouse: 980 mg/kg and 444 mg/kg, respectively.

Diazoxide Patient Information

No information avaliable

Diazoxide Organisms Affected

Humans and other mammals