Hypertonalum
Brand names,
Hypertonalum
Analogs
Hypertonalum
Brand Names Mixture
Hypertonalum
Chemical_Formula
C8H7ClN2O2S
Hypertonalum
RX_link
No information avaliable
Hypertonalum
fda sheet
Hypertonalum
msds (material safety sheet)
Hypertonalum
Synthesis Reference
No information avaliable
Hypertonalum
Molecular Weight
230.672 g/mol
Hypertonalum
Melting Point
330.5 oC
Hypertonalum
H2O Solubility
2850 mg/L
Hypertonalum
State
Solid
Hypertonalum
LogP
2.135
Hypertonalum
Dosage Forms
Oral capsules; Oral suspension
Hypertonalum
Indication
Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.
Hypertonalum
Pharmacology
Diazoxide is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. This switches off voltage-gated calcium ion channels which inhibits the generation of an action potential.
Hypertonalum
Absorption
Readily absorbed following oral administration.
Hypertonalum
side effects and Toxicity
Oral LD50 in rat and mouse: 980 mg/kg and 444 mg/kg, respectively.
Hypertonalum
Patient Information
No information avaliable
Hypertonalum
Organisms Affected
Humans and other mammals