SIGMA CHEMICAL CO -- DIAZOXIDE, D9035 -- 6505-00N093142
===================== Product Identification =====================
Product ID:DIAZOXIDE, D9035
MSDS Date:01/01/1999
FSC:6505
NIIN:00N093142
Status Code:A
MSDS Number: CJXGC
=== Responsible Party ===
Company Name:SIGMA CHEMICAL CO
Box:14508
City:ST LOUIS
State:MO
ZIP:63178
Country:US
Info Phone Num:314-771-5765
Emergency Phone Num:314-771-5765
CAGE:21076
=== Contractor Identification ===
Company Name:SIGMA CHEMICAL COMPANY
Address:3050 SPRUCE ST
Box:14508
City:ST LOUIS
State:MO
ZIP:63178
Country:US
Phone:314-771-5765
CAGE:21076
============= Composition/Information on Ingredients =============
Ingred Name:DIAZOXIDE
CAS:364-98-7
RTECS #:DK8185000
Other REC Limits:N/K
OSHA PEL:N/K
OSHA STEL:N/K
ACGIH TLV:N/K
ACGIH STEL:N/K
===================== Hazards Identification =====================
LD50 LC50 Mixture:SEE TOXICOLOGICAL INFORMATION.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: HARMFUL IF SWALLOWED. MAY BE
HARMFUL IF INHALED, IF ABSORBED THROUGH SKIN. CAUSES SKIN IRRIT.
IRRITATING TO MUCOUS MEMBRANES & UPPER RESPIRATORY TRACT. POSSIBLE
SENSITIZER. MAY CAUSE SODIUM & W ATER RETENTION, HYPERGLYCEMIA,
MYOCARDIAL & CEREBRAL ISCHEMIA, RASH, HYPERURICEMIA, ARRHYTHMIAS,
CONVULSIONS, SHOCK, NAUSEA, MENTAL DEPRESS, HYPERTENSION,
PANCREATITIS, TRANSIENT CATARACTS. CHRONIC: P OSSIBLE RISK OF
CONGENITAL MALFORMATION IN FETUS. TARGET ORGANS: VASCULAR SYSTEM,
PANCREAS, BLOOD, SMOOTH MUSCLE. TO THE BEST OF MANUFACTURER'S
KNOWLEDGE, THE CHEM, PHYSICAL & TOXICOLOGICAL PROPERTIES HAVE NOT
BEEN THOROUGHLY INVESTIGATED.
Effects of Overexposure:SEE HEALTH HAZARDS.
======================= First Aid Measures =======================
First Aid:EYES/SKIN: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF WATER
FOR AT LEAST 15 MINUTES, WHILE REMOVING CONTAMINATED CLOTHING AND
SHOES. INHALATION: REMOVE TO FRESH AIR. IF NOT BREATHING, GIVE
ARTIFICIAL R ESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
INGESTION: WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE REUSE.
===================== Fire Fighting Measures =====================
Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL POWDER OR
APPROPRIATE FOAM.
Fire Fighting Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS AND FULL PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
================== Accidental Release Measures ==================
Spill Release Procedures:WEAR NIOSH APPROVED RESPIRATOR, CHEMICAL
SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP,
PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST.
VENTILATE AREA AND WASH SPILL S ITE AFTER MATERIAL PICKUP IS
COMPLETE.
====================== Handling and Storage ======================
Handling and Storage Precautions:DO NOT BREATHE DUST. DO NOT GET IN
EYES, ON SKIN, ON CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE.
KEEP TIGHTLY CLOSED. STORE IN A COOL DRY PLACE.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:WEAR APPROPRIATE NIOSH APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYEWASH AND DELUGE SHOWER MEETING ANSI
DESIGN CRITERIA . PROTECTIVE CLOTHING.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
================== Physical/Chemical Properties ==================
Appearance and Odor:SOLID.
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS.
Hazardous Decomposition Products:TOXIC FUMES OF CARBON MONOXIDE, CARBON
DIOXIDE, NITROGEN OXIDES, SULFUR OXIDES.
=================== Toxicological Information ===================
Toxicological Information:RTECS # DK8185000 -
2H-1,2,4-BENZOTHIADIAZINE, 7-CHLORO-3-METHYL-, 1,1-DIOXIDE.
TOXICITY DATA: ORL-RAT LD50: 980 MG/KG; AIPTAK 143, 446, 1963.
IPR-RAT LD50: 510 MG/KG; AIPTAK 143, 446, 1963. ORL-MUS L D50: 444
MG/KG; JPETAB 136, 344, 1962. IPR-MUS LD50: 326 MG/KG; JPETAB 136,
344, 1962. IVN-MUS LD50: 228 MG/KG; JPETAB 136, 344, 1962. TARGET
ORGAN DATA: VASCULAR (BP LOWERING NOT CHARACTERIZED IN AUT ONOMIC
SECTION); EFFECTS ON EMBRYO OR FETUS (OTHER EFFECTS TO EMBRYO OR
FETUS). ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL
SUBSTANCES (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN
RTECS FOR COMPLETE INFORMATION.
===================== Ecological Information =====================
Ecological:DATA NOT YET AVAILABLE.
==================== Disposal Considerations ====================
Waste Disposal Methods:DATA NOT AVAILABLE. DISPOSE OF IN ACCORDANCE
WITH LOCAL, STATE, AND FEDERAL REGULATIONS .
=================== MSDS Transport Information ===================
Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORATION
INFORMATION.
===================== Regulatory Information =====================
Federal Regulatory Information:EUROPEAN INFORMATION: HARMFUL. R 63:
POSSIBLE RISK OF HARM TO THE UNBORN CHILD. R 22: HARMFUL IF
SWALLOWED. R 36/37/38: IRRITATING TO EYES, RESPIRATORY SYSTEM AND
SKIN. S 26: IN CASE OF CONTACT WITH E YES, RINSE IMMEDIATELY WITH
PLENTY OF WATER AND SEEK MEDICAL ADVICE. S 36: WEAR SUITABLE
PROTECTIVE CLOTHING. S 22: DO NOT BREATHE DUST. REVIEWS, STANDARDS,
AND REGULATIONS: OEL=MAK. NOES 1983: HZD X7 114; NIS 1; TNF 63; NOS
3; TNE 612; TFE 395.
State Regulatory Information:
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.