Dizoxide
Dizoxide Brand names, Dizoxide Analogs
Dizoxide Brand Names Mixture
- No information avaliable
Dizoxide Chemical_Formula
C8H7ClN2O2S
Dizoxide RX_link
No information avaliable
Dizoxide fda sheet
Dizoxide msds (material safety sheet)
Dizoxide Synthesis Reference
No information avaliable
Dizoxide Molecular Weight
230.672 g/mol
Dizoxide Melting Point
330.5 oC
Dizoxide H2O Solubility
2850 mg/L
Dizoxide State
Solid
Dizoxide LogP
2.135
Dizoxide Dosage Forms
Oral capsules; Oral suspension
Dizoxide Indication
Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.
Dizoxide Pharmacology
Diazoxide is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. This switches off voltage-gated calcium ion channels which inhibits the generation of an action potential.
Dizoxide Absorption
Readily absorbed following oral administration.
Dizoxide side effects and Toxicity
Oral LD50 in rat and mouse: 980 mg/kg and 444 mg/kg, respectively.
Dizoxide Patient Information
No information avaliable
Dizoxide Organisms Affected
Humans and other mammals
