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Dizoxide Brand names, Dizoxide Analogs

Dizoxide Brand Names Mixture

  • No information avaliable

Dizoxide Chemical_Formula

C8H7ClN2O2S

Dizoxide RX_link

No information avaliable

Dizoxide fda sheet

Dizoxide msds (material safety sheet)

Dizoxide MSDS

Dizoxide Synthesis Reference

No information avaliable

Dizoxide Molecular Weight

230.672 g/mol

Dizoxide Melting Point

330.5 oC

Dizoxide H2O Solubility

2850 mg/L

Dizoxide State

Solid

Dizoxide LogP

2.135

Dizoxide Dosage Forms

Oral capsules; Oral suspension

Dizoxide Indication

Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.

Dizoxide Pharmacology

Diazoxide is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. This switches off voltage-gated calcium ion channels which inhibits the generation of an action potential.

Dizoxide Absorption

Readily absorbed following oral administration.

Dizoxide side effects and Toxicity

Oral LD50 in rat and mouse: 980 mg/kg and 444 mg/kg, respectively.

Dizoxide Patient Information

No information avaliable

Dizoxide Organisms Affected

Humans and other mammals