Proglicem
Proglicem Brand names, Proglicem Analogs
Proglicem Brand Names Mixture
- No information avaliable
Proglicem Chemical_Formula
C8H7ClN2O2S
Proglicem RX_link
No information avaliable
Proglicem fda sheet
Proglicem msds (material safety sheet)
Proglicem Synthesis Reference
No information avaliable
Proglicem Molecular Weight
230.672 g/mol
Proglicem Melting Point
330.5 oC
Proglicem H2O Solubility
2850 mg/L
Proglicem State
Solid
Proglicem LogP
2.135
Proglicem Dosage Forms
Oral capsules; Oral suspension
Proglicem Indication
Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.
Proglicem Pharmacology
Diazoxide is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. This switches off voltage-gated calcium ion channels which inhibits the generation of an action potential.
Proglicem Absorption
Readily absorbed following oral administration.
Proglicem side effects and Toxicity
Oral LD50 in rat and mouse: 980 mg/kg and 444 mg/kg, respectively.
Proglicem Patient Information
No information avaliable
Proglicem Organisms Affected
Humans and other mammals
