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Clorazepate Brand names, Clorazepate Analogs

Clorazepate Brand Names Mixture

  • Dermadex Crm (Benzoic Acid + Benzyl Benzoate + Lindane + Salicylic Acid + Zinc Oxide + Zinc Undecylenate)

Clorazepate Chemical_Formula


Clorazepate RX_link

Clorazepate fda sheet

Clorazepate msds (material safety sheet)

Clorazepate Synthesis Reference

No information avaliable

Clorazepate Molecular Weight

314.723 g/mol

Clorazepate Melting Point

No information avaliable

Clorazepate H2O Solubility

Very soluble

Clorazepate State


Clorazepate LogP


Clorazepate Dosage Forms

Tablet (containing either 3.75 mg, 7.5 mg or 15 mg of clorazepate dipotassium for oral administration)

Clorazepate Indication

For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Also used as adjunctive therapy in the management of partial seizures and for the symptomatic relief of acute alcohol withdrawal.

Clorazepate Pharmacology

Clorazepate is a member of the group of drugs called benzodiazepines. Pharmacologically, clorazepate has the characteristics of the benzodiazepines. It has depressant effects on the central nervous system. The primary metabolite, nordiazepam, quickly appears in the blood stream. Studies in healthy men have shown that clorazenate has depressant effects on the central nervous system. Since orally administered clorazepate dipotassium is rapidly decarboxylated to form nordiazepam, there is essentially no circulating parent drug.

Clorazepate Absorption

Rapidly absorbed following oral administration (bioavailability is 91%).

Clorazepate side effects and Toxicity

Oral LD50 in rats is 1320 mg/kg. In monkeys, oral LD50 exceed 1600 mg/kg. Symptoms of overdose include confusion, coma, impaired coordination, sleepiness, and slowed reaction time.

Clorazepate Patient Information

Clorazepate Organisms Affected

Humans and other mammals