Gen-xene

• Anti-Anxiety Agents
• Anticonvulsants
• GABA Modulators
• ATC:N05BA05

• Chlorazepate
• Chlorazepic acid
• Clorazepate dipotassium
• Clorazepic acid
• Clorazepic acid [BAN]
• Gen-xene
• Tranxene

• Dermadex Crm (Benzoic Acid + Benzyl Benzoate + Lindane + Salicylic Acid + Zinc Oxide + Zinc Undecylenate)

C₁₆H₁₁ClN₂O₃

http://www.rxlist.com/cgi/generic2/clorazepate.htm

No information avaliable

314.723 g/mol

No information avaliable

Very soluble

Solid

2.327

Tablet (containing either 3.75 mg, 7.5 mg or 15 mg of clorazepate dipotassium for oral administration)

For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Also used as adjunctive therapy in the management of partial seizures and for the symptomatic relief of acute alcohol withdrawal.

Clorazepate is a member of the group of drugs called benzodiazepines. Pharmacologically, clorazepate has the characteristics of the benzodiazepines. It has depressant effects on the central nervous system. The primary metabolite, nordiazepam, quickly appears in the blood stream. Studies in healthy men have shown that clorazenate has depressant effects on the central nervous system. Since orally administered clorazepate dipotassium is rapidly decarboxylated to form nordiazepam, there is essentially no circulating parent drug.

Rapidly absorbed following oral administration (bioavailability is 91%).

Oral LD₅₀ in rats is 1320 mg/kg. In monkeys, oral LD₅₀ exceed 1600 mg/kg. Symptoms of overdose include confusion, coma, impaired coordination, sleepiness, and slowed reaction time.

Humans and other mammals