Chlorazepic acid
Brand names,
Chlorazepic acid
Analogs
Chlorazepic acid
Brand Names Mixture
- Dermadex Crm (Benzoic Acid + Benzyl Benzoate + Lindane + Salicylic Acid + Zinc Oxide + Zinc Undecylenate)
Chlorazepic acid
Chemical_Formula
C16H11ClN2O3
Chlorazepic acid
RX_link
http://www.rxlist.com/cgi/generic2/clorazepate.htm
Chlorazepic acid
fda sheet
Chlorazepic acid
msds (material safety sheet)
Chlorazepic acid
Synthesis Reference
No information avaliable
Chlorazepic acid
Molecular Weight
314.723 g/mol
Chlorazepic acid
Melting Point
No information avaliable
Chlorazepic acid
H2O Solubility
Very soluble
Chlorazepic acid
State
Solid
Chlorazepic acid
LogP
2.327
Chlorazepic acid
Dosage Forms
Tablet (containing either 3.75 mg, 7.5 mg or 15 mg of clorazepate dipotassium for oral administration)
Chlorazepic acid
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Also used as adjunctive therapy in the management of partial seizures and for the symptomatic relief of acute alcohol withdrawal.
Chlorazepic acid
Pharmacology
Clorazepate is a member of the group of drugs called benzodiazepines. Pharmacologically, clorazepate has the characteristics of the benzodiazepines. It has depressant effects on the central nervous system. The primary metabolite, nordiazepam, quickly appears in the blood stream. Studies in healthy men have shown that clorazenate has depressant effects on the central nervous system. Since orally administered clorazepate dipotassium is rapidly decarboxylated to form nordiazepam, there is essentially no circulating parent drug.
Chlorazepic acid
Absorption
Rapidly absorbed following oral administration (bioavailability is 91%).
Chlorazepic acid
side effects and Toxicity
Oral LD50 in rats is 1320 mg/kg. In monkeys, oral LD50 exceed 1600 mg/kg. Symptoms of overdose include confusion, coma, impaired coordination, sleepiness, and slowed reaction time.
Chlorazepic acid
Patient Information
Chlorazepic acid
Organisms Affected
Humans and other mammals