Clorazepic acid [BAN]

Clorazepic acid [BAN] Brand names, Clorazepic acid [BAN] Analogs

Clorazepic acid [BAN] Brand Names Mixture

Dermadex Crm (Benzoic Acid + Benzyl Benzoate + Lindane + Salicylic Acid + Zinc Oxide + Zinc Undecylenate)

Clorazepic acid [BAN] Chemical_Formula

C₁₆H₁₁ClN₂O₃

Clorazepic acid [BAN] RX_link

http://www.rxlist.com/cgi/generic2/clorazepate.htm

Clorazepic acid [BAN] fda sheet

Clorazepic acid [BAN] msds (material safety sheet)

Clorazepic acid [BAN] Synthesis Reference

No information avaliable

Clorazepic acid [BAN] Molecular Weight

314.723 g/mol

Clorazepic acid [BAN] Melting Point

No information avaliable

Clorazepic acid [BAN] H₂O Solubility

Very soluble

Clorazepic acid [BAN] State

Solid

Clorazepic acid [BAN] LogP

2.327

Clorazepic acid [BAN] Dosage Forms

Tablet (containing either 3.75 mg, 7.5 mg or 15 mg of clorazepate dipotassium for oral administration)

Clorazepic acid [BAN] Indication

For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Also used as adjunctive therapy in the management of partial seizures and for the symptomatic relief of acute alcohol withdrawal.

Clorazepic acid [BAN] Pharmacology

Clorazepate is a member of the group of drugs called benzodiazepines. Pharmacologically, clorazepate has the characteristics of the benzodiazepines. It has depressant effects on the central nervous system. The primary metabolite, nordiazepam, quickly appears in the blood stream. Studies in healthy men have shown that clorazenate has depressant effects on the central nervous system. Since orally administered clorazepate dipotassium is rapidly decarboxylated to form nordiazepam, there is essentially no circulating parent drug.

Clorazepic acid [BAN] Absorption

Rapidly absorbed following oral administration (bioavailability is 91%).

Clorazepic acid [BAN] side effects and Toxicity

Oral LD₅₀ in rats is 1320 mg/kg. In monkeys, oral LD₅₀ exceed 1600 mg/kg. Symptoms of overdose include confusion, coma, impaired coordination, sleepiness, and slowed reaction time.

Clorazepic acid [BAN] Patient Information

Clorazepic acid [BAN] Organisms Affected

Humans and other mammals