Clorazepate dipotassium
Clorazepate dipotassium Brand names, Clorazepate dipotassium Analogs
Clorazepate dipotassium Brand Names Mixture
- Dermadex Crm (Benzoic Acid + Benzyl Benzoate + Lindane + Salicylic Acid + Zinc Oxide + Zinc Undecylenate)
Clorazepate dipotassium Chemical_Formula
C16H11ClN2O3
Clorazepate dipotassium RX_link
http://www.rxlist.com/cgi/generic2/clorazepate.htm
Clorazepate dipotassium fda sheet
Clorazepate dipotassium msds (material safety sheet)
Clorazepate dipotassium Synthesis Reference
No information avaliable
Clorazepate dipotassium Molecular Weight
314.723 g/mol
Clorazepate dipotassium Melting Point
No information avaliable
Clorazepate dipotassium H2O Solubility
Very soluble
Clorazepate dipotassium State
Solid
Clorazepate dipotassium LogP
2.327
Clorazepate dipotassium Dosage Forms
Tablet (containing either 3.75 mg, 7.5 mg or 15 mg of clorazepate dipotassium for oral administration)
Clorazepate dipotassium Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Also used as adjunctive therapy in the management of partial seizures and for the symptomatic relief of acute alcohol withdrawal.
Clorazepate dipotassium Pharmacology
Clorazepate is a member of the group of drugs called benzodiazepines. Pharmacologically, clorazepate has the characteristics of the benzodiazepines. It has depressant effects on the central nervous system. The primary metabolite, nordiazepam, quickly appears in the blood stream. Studies in healthy men have shown that clorazenate has depressant effects on the central nervous system. Since orally administered clorazepate dipotassium is rapidly decarboxylated to form nordiazepam, there is essentially no circulating parent drug.
Clorazepate dipotassium Absorption
Rapidly absorbed following oral administration (bioavailability is 91%).
Clorazepate dipotassium side effects and Toxicity
Oral LD50 in rats is 1320 mg/kg. In monkeys, oral LD50 exceed 1600 mg/kg. Symptoms of overdose include confusion, coma, impaired coordination, sleepiness, and slowed reaction time.
Clorazepate dipotassium Patient Information
Clorazepate dipotassium Organisms Affected
Humans and other mammals
