Tranxene
Tranxene Brand names, Tranxene Analogs
Tranxene Brand Names Mixture
- Dermadex Crm (Benzoic Acid + Benzyl Benzoate + Lindane + Salicylic Acid + Zinc Oxide + Zinc Undecylenate)
Tranxene Chemical_Formula
C16H11ClN2O3
Tranxene RX_link
http://www.rxlist.com/cgi/generic2/clorazepate.htm
Tranxene fda sheet
Tranxene msds (material safety sheet)
Tranxene Synthesis Reference
No information avaliable
Tranxene Molecular Weight
314.723 g/mol
Tranxene Melting Point
No information avaliable
Tranxene H2O Solubility
Very soluble
Tranxene State
Solid
Tranxene LogP
2.327
Tranxene Dosage Forms
Tablet (containing either 3.75 mg, 7.5 mg or 15 mg of clorazepate dipotassium for oral administration)
Tranxene Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Also used as adjunctive therapy in the management of partial seizures and for the symptomatic relief of acute alcohol withdrawal.
Tranxene Pharmacology
Clorazepate is a member of the group of drugs called benzodiazepines. Pharmacologically, clorazepate has the characteristics of the benzodiazepines. It has depressant effects on the central nervous system. The primary metabolite, nordiazepam, quickly appears in the blood stream. Studies in healthy men have shown that clorazenate has depressant effects on the central nervous system. Since orally administered clorazepate dipotassium is rapidly decarboxylated to form nordiazepam, there is essentially no circulating parent drug.
Tranxene Absorption
Rapidly absorbed following oral administration (bioavailability is 91%).
Tranxene side effects and Toxicity
Oral LD50 in rats is 1320 mg/kg. In monkeys, oral LD50 exceed 1600 mg/kg. Symptoms of overdose include confusion, coma, impaired coordination, sleepiness, and slowed reaction time.
Tranxene Patient Information
Tranxene Organisms Affected
Humans and other mammals
