Carbinoxamine
Carbinoxamine Brand names, Carbinoxamine Analogs
Carbinoxamine Brand Names Mixture
- No information avaliable
Carbinoxamine Chemical_Formula
C16H19ClN2O
Carbinoxamine RX_link
http://www.rxlist.com/cgi/generic3/rondecsyr.htm
Carbinoxamine fda sheet
Carbinoxamine msds (material safety sheet)
Carbinoxamine Synthesis Reference
No information avaliable
Carbinoxamine Molecular Weight
290.788 g/mol
Carbinoxamine Melting Point
< 25 oC
Carbinoxamine H2O Solubility
No information avaliable
Carbinoxamine State
Liquid
Carbinoxamine LogP
2.979
Carbinoxamine Dosage Forms
Oral drops; Syrup; Tablet
Carbinoxamine Indication
For symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis.
Carbinoxamine Pharmacology
Carbinoxamine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, carbinoxamine competes with free histamine for binding at HA-receptor sites. Carbinoxamine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of carbinoxamine.
Carbinoxamine Absorption
No information avaliable
Carbinoxamine side effects and Toxicity
No information avaliable
Carbinoxamine Patient Information
Carbinoxamine Organisms Affected
Humans and other mammals
