Clistin
Brand names,
Clistin
Analogs
Clistin
Brand Names Mixture
Clistin
Chemical_Formula
C16H19ClN2O
Clistin
RX_link
http://www.rxlist.com/cgi/generic3/rondecsyr.htm
Clistin
fda sheet
Clistin
msds (material safety sheet)
Clistin
Synthesis Reference
No information avaliable
Clistin
Molecular Weight
290.788 g/mol
Clistin
Melting Point
< 25 oC
Clistin
H2O Solubility
No information avaliable
Clistin
State
Liquid
Clistin
LogP
2.979
Clistin
Dosage Forms
Oral drops; Syrup; Tablet
Clistin
Indication
For symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis.
Clistin
Pharmacology
Carbinoxamine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, carbinoxamine competes with free histamine for binding at HA-receptor sites. Carbinoxamine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of carbinoxamine.
Clistin
Absorption
No information avaliable
Clistin
side effects and Toxicity
No information avaliable
Clistin
Patient Information
Clistin
Organisms Affected
Humans and other mammals