Paracarbinoxamine
Paracarbinoxamine Brand names, Paracarbinoxamine Analogs
Paracarbinoxamine Brand Names Mixture
- No information avaliable
Paracarbinoxamine Chemical_Formula
C16H19ClN2O
Paracarbinoxamine RX_link
http://www.rxlist.com/cgi/generic3/rondecsyr.htm
Paracarbinoxamine fda sheet
Paracarbinoxamine msds (material safety sheet)
Paracarbinoxamine Synthesis Reference
No information avaliable
Paracarbinoxamine Molecular Weight
290.788 g/mol
Paracarbinoxamine Melting Point
< 25 oC
Paracarbinoxamine H2O Solubility
No information avaliable
Paracarbinoxamine State
Liquid
Paracarbinoxamine LogP
2.979
Paracarbinoxamine Dosage Forms
Oral drops; Syrup; Tablet
Paracarbinoxamine Indication
For symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis.
Paracarbinoxamine Pharmacology
Carbinoxamine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, carbinoxamine competes with free histamine for binding at HA-receptor sites. Carbinoxamine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of carbinoxamine.
Paracarbinoxamine Absorption
No information avaliable
Paracarbinoxamine side effects and Toxicity
No information avaliable
Paracarbinoxamine Patient Information
Paracarbinoxamine Organisms Affected
Humans and other mammals
