Rotoxamine
Rotoxamine Brand names, Rotoxamine Analogs
Rotoxamine Brand Names Mixture
- No information avaliable
Rotoxamine Chemical_Formula
C16H19ClN2O
Rotoxamine RX_link
http://www.rxlist.com/cgi/generic3/rondecsyr.htm
Rotoxamine fda sheet
Rotoxamine msds (material safety sheet)
Rotoxamine Synthesis Reference
No information avaliable
Rotoxamine Molecular Weight
290.788 g/mol
Rotoxamine Melting Point
< 25 oC
Rotoxamine H2O Solubility
No information avaliable
Rotoxamine State
Liquid
Rotoxamine LogP
2.979
Rotoxamine Dosage Forms
Oral drops; Syrup; Tablet
Rotoxamine Indication
For symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis.
Rotoxamine Pharmacology
Carbinoxamine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, carbinoxamine competes with free histamine for binding at HA-receptor sites. Carbinoxamine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of carbinoxamine.
Rotoxamine Absorption
No information avaliable
Rotoxamine side effects and Toxicity
No information avaliable
Rotoxamine Patient Information
Rotoxamine Organisms Affected
Humans and other mammals
