Paracarinoxamine
Paracarinoxamine Brand names, Paracarinoxamine Analogs
Paracarinoxamine Brand Names Mixture
- No information avaliable
Paracarinoxamine Chemical_Formula
C16H19ClN2O
Paracarinoxamine RX_link
http://www.rxlist.com/cgi/generic3/rondecsyr.htm
Paracarinoxamine fda sheet
Paracarinoxamine msds (material safety sheet)
Paracarinoxamine Synthesis Reference
No information avaliable
Paracarinoxamine Molecular Weight
290.788 g/mol
Paracarinoxamine Melting Point
< 25 oC
Paracarinoxamine H2O Solubility
No information avaliable
Paracarinoxamine State
Liquid
Paracarinoxamine LogP
2.979
Paracarinoxamine Dosage Forms
Oral drops; Syrup; Tablet
Paracarinoxamine Indication
For symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis.
Paracarinoxamine Pharmacology
Carbinoxamine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, carbinoxamine competes with free histamine for binding at HA-receptor sites. Carbinoxamine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of carbinoxamine.
Paracarinoxamine Absorption
No information avaliable
Paracarinoxamine side effects and Toxicity
No information avaliable
Paracarinoxamine Patient Information
Paracarinoxamine Organisms Affected
Humans and other mammals
