Twiston
Twiston Brand names, Twiston Analogs
Twiston Brand Names Mixture
- No information avaliable
Twiston Chemical_Formula
C16H19ClN2O
Twiston RX_link
http://www.rxlist.com/cgi/generic3/rondecsyr.htm
Twiston fda sheet
Twiston msds (material safety sheet)
Twiston Synthesis Reference
No information avaliable
Twiston Molecular Weight
290.788 g/mol
Twiston Melting Point
< 25 oC
Twiston H2O Solubility
No information avaliable
Twiston State
Liquid
Twiston LogP
2.979
Twiston Dosage Forms
Oral drops; Syrup; Tablet
Twiston Indication
For symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis.
Twiston Pharmacology
Carbinoxamine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, carbinoxamine competes with free histamine for binding at HA-receptor sites. Carbinoxamine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of carbinoxamine.
Twiston Absorption
No information avaliable
Twiston side effects and Toxicity
No information avaliable
Twiston Patient Information
Twiston Organisms Affected
Humans and other mammals
