Twiston

• Antihistamines
• ATC:R06AA08

• Allergefon
• Carbinoxamine Maleate
• Clistin
• Paracarbinoxamine
• Paracarinoxamine
• Rotoxamine
• Twiston

• No information avaliable

C₁₆H₁₉ClN₂O

http://www.rxlist.com/cgi/generic3/rondecsyr.htm

No information avaliable

290.788 g/mol

< 25 ^oC

No information avaliable

Liquid

2.979

Oral drops; Syrup; Tablet

For symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis.

Carbinoxamine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, carbinoxamine competes with free histamine for binding at HA-receptor sites. Carbinoxamine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of carbinoxamine.

No information avaliable

No information avaliable

Humans and other mammals