Carbinoxamine Maleate
Carbinoxamine Maleate Brand names, Carbinoxamine Maleate Analogs
Carbinoxamine Maleate Brand Names Mixture
- No information avaliable
Carbinoxamine Maleate Chemical_Formula
C16H19ClN2O
Carbinoxamine Maleate RX_link
http://www.rxlist.com/cgi/generic3/rondecsyr.htm
Carbinoxamine Maleate fda sheet
Carbinoxamine Maleate msds (material safety sheet)
Carbinoxamine Maleate Synthesis Reference
No information avaliable
Carbinoxamine Maleate Molecular Weight
290.788 g/mol
Carbinoxamine Maleate Melting Point
< 25 oC
Carbinoxamine Maleate H2O Solubility
No information avaliable
Carbinoxamine Maleate State
Liquid
Carbinoxamine Maleate LogP
2.979
Carbinoxamine Maleate Dosage Forms
Oral drops; Syrup; Tablet
Carbinoxamine Maleate Indication
For symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis.
Carbinoxamine Maleate Pharmacology
Carbinoxamine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, carbinoxamine competes with free histamine for binding at HA-receptor sites. Carbinoxamine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of carbinoxamine.
Carbinoxamine Maleate Absorption
No information avaliable
Carbinoxamine Maleate side effects and Toxicity
No information avaliable
Carbinoxamine Maleate Patient Information
Carbinoxamine Maleate Organisms Affected
Humans and other mammals
