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Buprenorphine Brand names, Buprenorphine Analogs

Buprenorphine Brand Names Mixture

  • No information avaliable

Buprenorphine Chemical_Formula


Buprenorphine RX_link


Buprenorphine fda sheet

Buprenorphine FDA

Buprenorphine msds (material safety sheet)

Buprenorphine Synthesis Reference

No information avaliable

Buprenorphine Molecular Weight

467.64 g/mol

Buprenorphine Melting Point

No information avaliable

Buprenorphine H2O Solubility

No information avaliable

Buprenorphine State


Buprenorphine LogP


Buprenorphine Dosage Forms

Tablet (sublingual)

Buprenorphine Indication

For the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.

Buprenorphine Pharmacology

Buprenorphine is a synthetic opioid analgesic and thebaine derivative, with a longer duration of action than morphine. Buprenorphine interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, buprenorphine exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Buprenorphine may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Buprenorphine depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.

Buprenorphine Absorption

31% bioavailability (sublingual)

Buprenorphine side effects and Toxicity

Manifestations of acute overdose include pinpoint pupils, sedation, hypotension, respiratory depression and death.

Buprenorphine Patient Information

Buprenorphine Organisms Affected

Humans and other mammals