Buprenorphinum [Inn-Latin] en es it fr

Buprenorphinum [Inn-Latin] Brand names, Buprenorphinum [Inn-Latin] Analogs

Buprenorphinum [Inn-Latin] Brand Names Mixture

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Buprenorphinum [Inn-Latin] Chemical_Formula


Buprenorphinum [Inn-Latin] RX_link


Buprenorphinum [Inn-Latin] fda sheet

Buprenorphinum_[Inn-Latin] FDA

Buprenorphinum [Inn-Latin] msds (material safety sheet)

Buprenorphinum [Inn-Latin] Synthesis Reference

No information avaliable

Buprenorphinum [Inn-Latin] Molecular Weight

467.64 g/mol

Buprenorphinum [Inn-Latin] Melting Point

No information avaliable

Buprenorphinum [Inn-Latin] H2O Solubility

No information avaliable

Buprenorphinum [Inn-Latin] State


Buprenorphinum [Inn-Latin] LogP


Buprenorphinum [Inn-Latin] Dosage Forms

Tablet (sublingual)

Buprenorphinum [Inn-Latin] Indication

For the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.

Buprenorphinum [Inn-Latin] Pharmacology

Buprenorphine is a synthetic opioid analgesic and thebaine derivative, with a longer duration of action than morphine. Buprenorphine interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, buprenorphine exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Buprenorphine may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Buprenorphine depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.

Buprenorphinum [Inn-Latin] Absorption

31% bioavailability (sublingual)

Buprenorphinum [Inn-Latin] side effects and Toxicity

Manifestations of acute overdose include pinpoint pupils, sedation, hypotension, respiratory depression and death.

Buprenorphinum [Inn-Latin] Patient Information

Buprenorphinum [Inn-Latin] Organisms Affected

Humans and other mammals